ĐÁNH GIÁ KẾT QUẢ PHẪU THUẬT CẮT UNG THƯ LƯỠI TRONG ĐIỀU TRỊ UNG THƯ LƯỠI TẠI BỆNH VIỆN ĐẠI HỌC Y DƯỢC THÀNH PHỐ HỒ CHÍ MINH TỪ NĂM 2017 ĐẾN NĂM 2022

Abstract

Aim: To evaluate survival rates, recurrence rates, distant metastasis, and to assess the quality of life in patients following tongue cancer resection surgery. Subjects and Methods: This is a retrospective study. We collected 71 cases of squamous cell carcinoma of the tongue with complete medical records, histories, physical examinations, imaging, and multidisciplinary consultations prior to surgery. These patients underwent tongue cancer resection between January 2017 and January 2022. Results: The average age of the study sample was 56,9 ± 12,3 years, with a male-to-female ratio of 1.96:1. The tumors were primarily located on the free margin of the tongue (77,5%) with an ulcerative and exophytic surface (52,7%), predominantly in stage IVA (33,8%). The recurrence rate after surgery was 31%, mainly occurring in the cervical lymph nodes (50%). The recurrence rate in the T4 group was 12,5 times  higher than  in the T2 group, and in the  N2c group, it was  5,9 times higher than in the N0 group. Most recurrences occurred within the first 2 years after treatment. The postoperative mortality rate was 19,7%, primarily due to lymph node recurrence or distant metastasis (50%). The overall survival (OS) rate was 96,9% at 1 year and 75,5% at 5 years. Disease-free survival (DFS) rates were 87,3% at 1 year and 68,4% at 5 years. Scores related to "swallowing disorders," "speech disorders," "eating ability," "communication ability," "sexual dysfunction," and "oral health status" were all above 20 points, indicating a significant impact on the patients' quality of life. Conclusion: Surgery is an effective treatment for stage I-II tongue cancer. However, the recurrence rate remains high in stage III-IV cases, even after surgery combined with adjuvant therapy. Patients’ quality of life post-surgery is affected, including speech, chewing, and swallowing functions.