THE CHARACTERISTICS OF GASTRIC - DUODENAL LESIONS ON ENDOSCOPY OF MUSCULOSKELETAL PATIENTS USING LONG-TERM GLUCOCORTICOID AT THAI NGUYEN NATIONAL HOSPITAL

Lâm Tín Phan, Thị Bình Lưu, Tiến Thăng Vũ

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Abstract

Objective: To describe the characteristics of gastric and duodenal lesions on endoscopy of musculoskeletal patients using long-term glucocorticoid at Thai Nguyen National Hospital. Subjects and methods: A cross-sectional descriptive study was conducted on 117 musculoskeletal patients who are being treated with glucocorticoid at Thai Nguyen National Hospital. Results: The proportion of patients aged 60-69 years old was 17.9%; from 70-79 years old was 47.0%. The proportion of glucocorticoid use ≤12 months was 49.6% and >12 months was 50.4%; the mean prednisolone equivalent dose was 34.73 ± 20.79 mg. The proportion of Methylprednisolone using was 69.2%; Dexamethasone 25.6% and Hydrocortisone 4.3%. The proportion of oral using was 49.6%; intravenous injection was 27.4%. The proportion of patients with gastric mucosal lesions was 26.5%; duodenal 3.4%; overall lesions was 27.4%. The proportion of gastric edema was 12.0%; duodenal 0.9%; overall lesions was 12.8%. The proportion of gastric congestion was 22.0%; duodenal 1.7% and overall lesions 23.1%. The proportion of Helicobacter Pylori infection was 22.2%. Conclusion: The proportion of gastric-duodenal lesions on endoscopy of musculoskeletal patients using long-term glucocorticoid is relatively high.

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References

Bộ Y tế (2022), Dược thư quốc gia Việt Nam (Tái bản lần thứ ba), Bộ Y tế, Hà Nội.
2. Vũ Đình Hùng (2012), Nghiên cứu rối loạn trên bệnh nhân lupus ban đỏ hệ thống sử dụng glucocorticoid kéo dài tại Bệnh viện Bạch Mai, Khóa luận tốt nghiệp Bác sĩ Y khoa, Trường Đại học Y Hà Nội.
3. Lê Thị Thanh Ngà (2021), Nghiên cứu tổn thương dạ dày tá tràng ở bệnh nhân viêm khớp dạng thấp có sử dụng glucocorticoid, Luận văn Thạc sĩ Y học, Trường Đại học Y Hà Nội.
4. Lê Thị Thanh Ngà, Hoàng Văn Dũng, Nguyễn Hoài Nam (2021), "Đặc điểm tổn thương dạ dày-tá tràng ở bệnh nhân viêm khớp dạng thấp có sử dụng glucocorticoid", Tạp chí Y học Việt Nam, 506 (1), tr. 249-253.
5. Lê Ngọc Quý (2013), Nghiên cứu đặc điểm siêu âm Doppler năng lượng khớp cổ tay bệnh nhân viêm khớp dạng thấp, Luận văn Thạc sĩ Y học, Trường Đại học Y Hà Nội.
6. Orr C.K., Najm A., Young F., et al. (2018), "The Utility and Limitations of CRP, ESR and DAS28-CRP in Appraising Disease Activity in Rheumatoid Arthritis", Front Med (Lausanne), 5 pp. 185.
7. Pundir V., Pundir J., Lancaster G., et al. (2016), "Role of corticosteroids in Functional Endoscopic Sinus Surgery--a systematic review and meta-analysis", Rhinology, 54 (1), pp. 3-19.
8. Tsujimoto Saki, Mokuda Sho, Matoba Kenichiro, et al. (2018), "The prevalence of endoscopic gastric mucosal damage in patients with rheumatoid arthritis", PLOS ONE, 13 (7), pp. e0200023.