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EVALUATION OF THE MODEL FOR END STAGE LIVER DISEASE (MELD) SCORE, THE MELD SODIUM SCORE IN CIRRHOSIS PATIENTS WITH COMPLICATIONS
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Abstract
Aims: To evaluate the value of the MELD, MELD Na score in patients with cirrhosis and its complications. Subjects and methods: The prospective descriptive study was conducted at Department of Gastroenterology Bach Mai Hospital from July 2019 to March 2020. Research population: patients werediagnosed with cirrhosis and complications. Results and conclusion: There were 387 patients were recruited in our study. Mean MELD, MELD Na scores in the group of patients with GI bleeding were (13.15 ± 5.15), (15.05 ± 5.8), respectively which were lower than the group of patients without GI bleeding (21.03 ± 7.06), (23.78 ± 7.51); p <0.001 and it is not significant to anticipate complications with AUC <0.5. Mean MELD, MELD Na scores in the group of patients with hepatic encephalopathy were (21.16 ± 7.85), (23.76 ± 7.94), respectively, which were higher than the group of patients without hepatic encephalopathy (12.93 ± 4.57), (14.85 ± 5.46); p <0.001 and it’s slight significance to predict hepatic encephalopathy complications with AUC <0.7. Mean MELD, MELD Na scores in the group of patients with spontaneous bacterial peritonitis (SBP) were (18.06 ± 6.82) and (20.8 ± 7.32), respectively, which were higher than the group of patients without SBP (14.15 ± 6.15), (16.11 ± 6.82); p <0.001 and this is of significance to predict SBP complications with AUC were 0.701 and 0.725. Mean MELD, MELD Na scores in the group of patients with hepatorenal syndrome (HRS) were (27.94 ± 9.13) and (30.37 ± 8.39), which were higher than the group of patients without HRS (14.08 ± 5.56), (16.13 ± 6.38); p <0.001 and it is of significance to anticipate HRS complications with AUC were 0.995 and 0.901. Mean MELD, MELD Na scores in the group of patients with two or more complications were (20.23 ± 8.89) and (22.55 ± 8.69), respectively which were higher than the group of patients with only one complication (13.53 ± 5.04), (15.54 ± 6.04); p <0.001 and this is of significance to predict number of complications with AUC were 0.744 and 0.739, respectively.
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Keywords
MELD, MELD Na, cirrhosis with complications
References
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