ĐẶC ĐIỂM CỘNG HƯỞNG TỪ CỦA PHỔ BỆNH VIÊM TỦY THỊ THẦN KINH

Abstract

Objective: To describe the magnetic resonance imaging (MRI) characteristics of patients with neuromyelitis optica spectrum disorder (NMOSD). Subjects and Methods: We study 42 patients who were confirmed NMOSD diagnosis based on the 2015 consensus criteria. All patients underwent magnetic resonance imaging of the brain and spinal cord. Results: The amounts of patients who had abnormalities of the spinal cord, brain, both brain, and spinal cord, and optic nerve were 85.7%, 42.9%, 33.3%, and 23.8% respectively. On the brain MRI, the percentage of injury on the periependymal dorsal brainstem /cerebellum dorsal medulla was highest and accounted for 26.2%, followed by the dorsal medulla with 19%; the hypothalamus, the third ventricle periependymal (16,7%); the surrounding of the lateral ventricles (14,3%) and the white matter lesions adjacent to the occipital horn of the lateral ventricles (4.8%). 100% of spinal cord lesions were seen in the central, 52,8% in the cervical spinal cord and mostly was three or above vertebral segment in length (83.3%). In the group of patients with AQP4 positive, the abnormality was 86.1%. 50% of cases had cord edema while 73.8% of cases had contrast enhancement injury. Conclusion: In NMOSD, MRI lesions are not only in the spinal cord and optic nerve but also in the brain: brainstem, diencephalic and cerebral hemispheres.