METANEPHRIC ADENOMA – A RARE CASE REPORT

Cảnh Phạm Hồng, Sơn Chu Hồng, Linh Trần Thị, Minh Trần Ngọc

Main Article Content

Abstract

Metanephric adenoma (MA) is a sporadic benign tumor, accounting for only 0.2-0.7% of renal epithelial tumors, often difficult to distinguish from malignant tumors through imaging, accurate diagnosis mainly based on pathology and immunohistochemistry. This report describes the case of a 46-year-old female patient who accidentally discovered a left renal tumor during a routine health check. CT scan showed a homogeneous, well-defined mass with no necrosis or hemorrhage. Percutaneous biopsy under ultrasound guidance confirmed the diagnosis of MA. The patient was treated conservatively and followed up periodically. Through this clinical case, we would like to discuss the characteristics of metanephric adenoma, the role of preoperative biopsy, and some tests in diagnosis and treatment orientation, especially studies on BRAF V600E mutation, with the hope of opening up the potential for more straightforward and more accurate diagnosis in the future.

Article Details

References

1. Zhang L, Gao X, Li R, et al. Experience of diagnosis and management of metanephric adenoma: retrospectively analysis of 10 cases and a literature review. Translational Andrology and Urology. 2020;9(4): 1661669-1661669. doi:10. 21037/tau-19-912
2. Weerakkody Y. Metanephric adenoma of the kidney | Radiology Reference Article | Radiopaedia.org. Radiopaedia. doi:10.53347/rID-17858
3. Brown JA, Anderl KL, Borell TJ, Qian J, Bostwick DG, Jenkins RB. Simultaneous chromosome 7 and 17 gain and sex chromosome loss provide evidence that renal metanephric adenoma is related to papillary renal cell carcinoma. J Urol. 1997;158(2):370-374.
4. Yan J, Cheng JL, Li CF, et al. The findings of CT and MRI in patients with metanephric adenoma. Diagn Pathol. 2016;11:104. doi:10. 1186/s13000-016-0535-x
5. Metanephric adenoma and solid variant of papillary renal cell carcinoma: common and distinctive features - Mantoan Padilha - 2013 - Histopathology - Wiley Online Library. Accessed June 17, 2024. https://onlinelibrary. wiley.com/doi/abs/10.1111/his.12106
6. Delzongle M, Boukamel S, Kemeny F, et al. Metanephric adenoma: MR imaging features with histopathological correlation. Diagn Interv Imaging. 2015;96(4): 387-390. doi:10.1016/j.diii. 2014.11.005
7. Kinney SN, Eble JN, Hes O, et al. Metanephric adenoma: the utility of immunohistochemical and cytogenetic analyses in differential diagnosis, including solid variant papillary renal cell carcinoma and epithelial-predominant nephroblastoma. Mod Pathol. 2015;28(9):1236-1248. doi:10.1038/modpathol.2015.81