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Date Published: 02/04/2025
Abstract Views: 74
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DOI: https://doi.org/10.51298/vmj.v547i3.13203
Issue
Vol. 547 No. 3 (2025)
Section
Các bài báo
How to Cite
Hoàng Thị Ngọc, T., Nguyễn Tiến, D., Bùi Thị Thu, H., & Hồ Cẩm, T. (2025). THE IMMUNE RESPONSE THROUGH IL-2 EXPRESSION IN ACTIVATED T CELLS WITH HBV DNA IN PREGNANT WOMEN WITH HBsAg(+). Vietnam Medical Journal, 547(3). https://doi.org/10.51298/vmj.v547i3.13203

THE IMMUNE RESPONSE THROUGH IL-2 EXPRESSION IN ACTIVATED T CELLS WITH HBV DNA IN PREGNANT WOMEN WITH HBsAg(+)

Trâm Hoàng Thị Ngọc, Dũng Nguyễn Tiến, Hương Bùi Thị Thu, Tú Hồ Cẩm

Main Article Content

Abstract

Immune response studies on the HBV infected pregnancy women, especially T cell immune responses, are of interest. Objective: To investigate the relationship between the ability of activated T cells to secrete IL-2 and HBV DNA in pregnant women with HBsAg (+). Subjects: 80 pregnant women with HBsAg (+) and anti-HBc IgM (-) who gave birth from January 2019 to December 2022. Study design: Cross-sectional. Results: The mean age was 27.6 ± 4.7 years. HBV DNA ≥5x107 (copies/mL) accounted for 40%. The mean value of the number of IL-2 fluorescence spots was similar when using two types of antigens (LEP and CP). In the T cell-mediated immune response to HBV antigen (LEP, CP), IL-2 was positively correlated with HBV DNA (r=0.495, r=0.255, p<0.01).

Article Details

Keywords

HBV DNA, IL-2, T Cell, pregnancy women

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