ASSESSMENT OF EFFECTIVENESS OF NEOSTIGMINE AND ATROPINE FOR THE TREATMENT OF HEADACHE AFTER SPINAL OR EPIDURAL ANAESTHESIA IN OBSTETRIC

Lương Thị Hoài Khanh1,, Nguyễn Duy Ánh2, Nguyễn Đức Lam3
1 Nghe An Obstetrics and Pediatrics Hospital
2 Hanoi Obstetrics and Pediatrics Hospital
3 Hanoi Medical University

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Abstract

The objective: To evaluate the efficacy of Neostigmine and Atropine for the treatment of headache after spinal or epidural anaesthesia in obstetrics. Sixty women havingheadache after spinal or epidural anesthesia, eligible for research, were randomly selected to receive treatment with Neostigmine 20mcg/kg + Atropine 10mcg/kg or Paracetamol 1g. The results showed that the average VAS Score when the patient sat upright for 15 minutes is statistically significant different between the 2 groups (p < 0.05) at the time of injection 6 hours, 12 hours, 24 hours, 36 hours, 48 hours, 72 hours after injection. In the Neostigmine and Atropine group, no patient needed an epidural blood patch while in the Paracetamol group there were 6 patients (p<0.05).

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References

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