Article Sidebar
Views PDF: 158
EVALUATION OF THERAPEUTIC OF EFFECTIVENESS OF LACTULOSE ENEMA IN HEPATIC ENCEPHALOPATHY
Main Article Content
Abstract
Objective: We aimed to determine the effect of lactulose enema for treatment hepatic encephalopathy patients base on clinical and laboratory parameters. Subjects and methods: A total of 32 patients with hepatic encephalopathy treated with lactulose enema, West Haven Criteria was applied. Results: For overall response rate of the 32 patients who underwent lactulose enema, improvement in serum NH3 level was 84.4% and 15,6% not improvement. In term reversible neuropsychiatric was 53.1% patients. West Haven grade was improvement in 53.1%. Conclusion: Administration of lactulose enematreatment was seen to improve serum NH3 level and provide better outcome in hepatic encephalopathy patients.
Article Details
Keywords
Lactulose, hepatic encephalopathy patients, cirrhosis
References
2. Bhatia V, Singh R, Acharya SK: Predictive value of arterial ammonia for complications and outcome in acute liver failure. Gut 2006, 55(1):98-104.
3. Bohra A, Worland T, Hui S, Terbah R, Farrell A, Robertson M: Prognostic significance of hepatic encephalopathy in patients with cirrhosis treated with current standards of care. World journal of gastroenterology 2020, 26(18):2221-2231.
4. Said VJ, Garcia-Trujillo E: Beyond Lactulose: Treatment Options for Hepatic Encephalopathy. Gastroenterology nursing : the official journal of the Society of Gastroenterology Nurses and Associates 2019, 42(3):277-285.
5. Hadjihambi A, Arias N, Sheikh M, Jalan R: Hepatic encephalopathy: a critical current review. Hepatology international 2018, 12(Suppl 1):135-147.
6. Sharma BC, Sharma P, Lunia MK, Srivastava S, Goyal R, Sarin SK: A randomized, double-blind, controlled trial comparing rifaximin plus lactulose with lactulose alone in treatment of overt hepatic encephalopathy. The American journal of gastroenterology 2013, 108(9):1458-1463.
7. Paik YH, Lee KS, Han KH, Song KH, Kim MH, Moon BS, Ahn SH, Lee SJ, Park HJ, Lee DK et al: Comparison of rifaximin and lactulose for the treatment of hepatic encephalopathy: a prospective randomized study. Yonsei medical journal 2005, 46(3):399-407.