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THE RESULTS OF AMNIOTIC MEMBRANE TRANSPLANTATION FOR SYMPTOMATIC BULLOUS KERATOPATHY
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Abstract
Purpose: To evaluate the effectiveness of amniotic membrane transplantation (AMT) in relieving pain and discomfort in patients with symptomatic bullous keratopathy and poor visual potential. Methods: A prospective study of a case series, including 12 eyes (12 patients) with painful bullous keratopathy and poor visual potential. Amniotic membrane transplantation was performed. Pain relief, epithelial healing, and visual changes were analyzed. Results: The mean follow-up was 45,5 ± 43,4 (range 2 to 157 weeks). Pain relief was achieved in 91,7%, of which 75% were completely free of pain. Associated symptoms subsided significantly in all patients, including foreign body sensation in 1 (8,3%), no photophobia (0,0%), and tearing in 4 (33,3%) eyes. Vision improved in 2 (16,7%) patients. Complete epithelialization in all eyes at 6 weeks. One eye required evisceration due to ulceration and glaucoma 10 months after AMT. Conclusion: Amniotic membrane transplantation was a safe and effective treatment modality of pain relief in the eyes with symptomatic bullous keratopathy. Further studies and comparisons of AMT and other treatments are needed.
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Keywords
Amniotic membrane transplantation, Bullous keratopathy, Painful.
References
2. Espana EM, Grueterich M, Sandoval H, và cộng sự. Amniotic membrane transplantation for bullous keratopathy in eyes with poor visual potential. J Cataract Refract Surg. 2003; 29: p.279–284.
3. Gregory ME, Spiteri-Cornish K, Hegarty B và cộng sự. Combined amniotic membrane transplant and anterior stromal puncture in painful bullous keratopathy: clinical outcome and confocal microscopy. Can J Ophthalmol. 2011; 46: p.169–174.
4. Paris F.S, E. D. Gonçalves, M. S. de Q. Campos và cộng sự. Amniotic membrane transplantation versus anterior stromal puncture in bullous keratopathy: a comparative study. Br J Ophthalmol. 2013; 97: p.980–984.
5. Pires RT, Tseng SC, Prabhasawat P, và cộng sự. Amniotic membrane transplantation for symptomatic bullous keratopathy. Arch Ophthalmol. 1999; Pp.117:1291–1297.
6. Onur F, Melis P, Özlem B. S. Palliative Efficacy of Intrastromal Amniotic Membrane Procedure in Symptomatic Bullous Keratopathy Patients. Turk J Ophthalmol. 2022;52:162-167.
7. Srinivas S, Mavrikakis E, Jenkins C. Amniotic membrane transplantation for painful bullous keratopathy. European Journal of Ophthalmology / Vol. 17 no. 1, 2007; p.7-10
8. Siu GDYoung AL. Cheng ll. Long-term Symptomatic Relief Of Bullous Keratopathy with Amniotic Membrane Transplant. Int Ophthalmol. 2015; 35: p777–783.