NGHIÊN CỨU MẬT ĐỘ XƯƠNG TRÊN BỆNH NHÂN CAO TUỔI ĐÁI THÁO ĐƯỜNG TÍP 2

Abstract

Objective: Study the relationship between bone mineral density (BMD) and related factors in older adults with and without type 2 diabetes mellitus (T2DM). Subjects and Methods: Older adults aged ≥ 60 years visiting the Rheumatology and Geriatrics clinics at University of Medicine Center, Ho Chi Minh City, from September 2024 to December 2024. Data was collected using a survey questionnaire, including measurements of height and weight, biochemical tests and BMD. Results: Older adults with T2DM had higher BMD compared to those without T2DM (0.819 ± 0.19 g/cm² vs. 0.751 ± 0.16 g/cm², p = 0.004). Most older adults with T2DM had a higher incidence of comorbidities (particularly hypertension, dyslipidemia and ischemic heart disease), polypharmacy, dependence on activities of daily living (ADLs) and frailty compared to those without T2DM. Multivariate linear regression analysis revealed that factors associated with BMD included age (β = -0.263; p < 0.001), female gender (β = -0.284; p < 0.001), height (β = 0.159; p = 0.014), BMI (β = 0.239; p < 0.001) and T2DM (β = 0.222; p < 0.001). Conclusion: BMD in older adults with T2DM is higher than in those without T2DM. Age and female gender are inversely correlated with BMD, while height, BMI and T2DM are positively correlated with BMD.