NGHIÊN CỨU MỐI TƯƠNG QUAN GIỮA THANG ĐIỂM MỨC ĐỘ TỔN THƯƠNG PHỔI TRÊN HÌNH ẢNH CẮT LỚP VI TÍNH VỚI MỨC ĐỘ NẶNG BỆNH COVID - 19

Abstract

Objective: To analyze the correlation between the total CT severity score (CTSS) on chest CT and the severity of COVID-19. Subjects and Methods: This retrospective descriptive study included 180 patients who were confirmed to have COVID-19 by reverse transcription polymerase chain reaction (RT-PCR). All patients had complete medical history records in the electronic medical system and underwent chest CT imaging upon hospital admission at the COVID-19 Treatment Hospital of Hanoi Medical University Hospital between September 2021 and February 2023. Results: The mean CTSS scores for the mild, moderate, severe, and critical disease groups were 6.5±3.78, 13.29±3.84, 20.28±4.26, and 21.01±3.75, respectively. There was a statistically significant difference in mean CTSS scores between the mild and moderate groups, as well as between the moderate and severe groups (p < 0.001). However, the difference between the severe and critical groups was not statistically significant (p = 0.670). The CTSS score on chest CT had predictive value for severe disease, with a sensitivity of 80% and a specificity of 85.2% at a cutoff value of 15.5. It also had predictive value for critical disease, with a sensitivity of 87.5% and a specificity of 82.2% at a cutoff value of 16.5. However, the CTSS score had no prognostic value for mild and moderate COVID-19 cases (area under the curve [AUC] = 0.065). Conclusion: The CTSS score on chest CT is strongly correlated with the severity of COVID-19. The CTSS score has high sensitivity and specificity in predicting severe and critical disease, with thresholds of 15.5 for severe cases and 16.5 for critical cases.