THE VALUE OF GLOBAL LONGITUDINAL STRAIN VIA MYOCARDIAL SPECKLE TRACKING ECHOCARDIOGRAPHY IN PREDICTING SIGNIFICANT CORONARY ARTERY STENOSIS IN PATIENTS WITH CHRONIC CORONARY SYNDROME

Trí Nghĩa Phù, Huỳnh Xuân Nữ Phan, Thế Bảo Nguyễn, Thái Hòa Nguyễn

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Abstract

Background: Global longitudinal strain (GLS) of the left ventricle assessed by myocardial speckle tracking echocardiography has been demonstrated to be associated with coronary artery disease in several international studies. However, data in Vietnam remains limited. Objectives: To analyze the predictive capability of GLS via myocardial speckle tracking echocardiography for significant coronary artery stenosis in patients with chronic coronary syndrome. Materials and methods: A cross-sectional descriptive study was conducted on 40 patients suspected of having chronic coronary syndrome who visited Can Tho City General Hospital and Can Tho University of Medicine and Pharmacy Hospital from March 2023 to February 2025. Results: Regarding general characteristics, the male-to-female ratio was 1, with an average age of 66.0 ± 10.3 years. The values of left ventricular longitudinal strain parameters in 40 patients with chronic coronary syndrome followed a normal distribution, with global longitudinal strain (GLS-avg %) recorded at -15.30 ± 4.47. In terms of the distribution of significant coronary artery stenosis branches, three-fifths of the subjects had at least one stenotic branch, with two-vessel disease being the most prevalent at 30.0%. The global longitudinal strain parameters showed a decreasing trend with the increasing number of significantly stenotic branches, being lowest in the group with three-vessel disease. The observed differences were statistically significant (p < 0.05). The global longitudinal strain demonstrated a good predictive ability for significant coronary artery stenosis, with an area under the curve (AUC) of 0.846 (95% CI: 0.717-0.976). Conclusion: Global longitudinal strain tends to decrease as the number of affected coronary arteries increases. GLS initially shows good predictive value for significant coronary artery stenosis in patients with chronic coronary syndrome.

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References

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