PREVALENCE OF OSA IN NON-VALVULAR ATRIAL FIBRILLATION PATIENTS

Ngọc Phương Thư Nguyễn, Hiệp Hồ Dương, Thanh Phương Thượng, Thị Lệ Trang Nguyễn, Thanh Tuyền Trần, Đan Quế Bùi, Thành Nam Tống, Thị Trang Dương, Tuấn Vũ Nguyễn

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Abstract

Introduction: Atrial fibrillation (AF) is the most common cardiac arrhythmia in adults and is often referred to as a silent global cardiovascular epidemic of the 21st century. The complexity of managing AF comes not only from its high mortality rate but also from the interplay of various comorbidities. Among these, obstructive sleep apnea (OSA) is considered as a significant comorbidity and one of the most effectively modifiable factors to improve AF management. Early detection and treatment of OSA in AF patients not only optimizes treatment strategies but also improves prognosis and reduce mortality risk. In Vietnam, the overall understanding of the relationship between OSA and non-valvular AF remains limited. Based on this reality, this study was conducted in the General Cardiology Department of 115 People's Hospital to determine the prevalence of OSA in patients with non-valvular AF, aiming to provide a scientific basis for developing more comprehensive and effective AF treatment strategies. Objective: To investigate the prevalence of OSA in patients with non-valvular atrial fibrillation. Methods: A cross-sectional study was conducted on 126 patients with non-valvular atrial fibrillation (AF) at the General Cardiology Department of 115 People's Hospital from October 2023 to June 2024. Obstructive sleep apnea (OSA) was diagnosed using the Apnea Link device (ResMed) based on the criteria outlined in the third edition of the International Classification of Sleep Disorders (ICSD-3)1. Respiratory events were scored according to the 2016 recommendations of the American Academy of Sleep Medicine2. Demographic, anthropometric, and clinical characteristics were collected using a pre-designed questionnaire. Results: The median age of the patients was 61 years, with males accounting for 45.2% of the study population. The prevalence of OSA in patients with non-valvular AF was 74.6%, with mild, moderate, and severe cases accounting for 29.4%, 23%, and 22.2%, respectively. Conclusion: The prevalence of OSA in patients with non-valvular AF is high. Physicians should actively screen for OSA in patients with non-valvular AF to avoid missed diagnoses and to develop appropriate treatment strategies, thereby reducing cardiovascular complications associated with both AF and OSA. Additionally, enhancing patient education and communication to promote early recognition of OSA symptoms is essential.

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References

Medicine AAoS. International classification of sleep disorders— third edition (ICSD-3). Darien, Illinois. 2014.
2. AASM Manual for the Scoring of Sleep and Associated Events, Version 2.3 - April 1, 2016
3. Gami AS; Pressman G; Caples SM et al (2004), "Association of atrial fibrillation and obstructive sleep apnea", Circulation. 110(4), tr. 364-7.
4. Abumuamar AM; Dorian P; Newman D et al (2018), "The prevalence of obstructive sleep apnea in patients with atrial fibrillation", Clin Cardiol. 41(5), tr. 601-607.
5. Senaratna C, Perret J, Lodge C, et al. Prevalence of obstructive sleep apnea in the general population: A systematic review. Sleep Medicine Reviews. 2017;34:70-81.
6. Hoang Anh Tien, Mai Tran Phuoc Loc, Tran Viet An. Sleep Apnea Syndrome in Patients with Atrial Fibrillation. Springer Nature Switzerland AG 2022. 2022;8th International Conference on the Development of Biomedical Engineering in Vietnam, IFMBE Proceedings 8.
7. Shapira Daniels A; Mohanty S; Contreras Valdes FM et al (2020), "Prevalence of Undiagnosed Sleep Apnea in Patients With Atrial Fibrillation and its Impact on Therapy", JACC Clin Electrophysiol. 6(12), tr. 1499-1506.
8. Ibdah R, Zaitoun K, Altawalbeh R, et al. Prevalence of Obstructive Sleep Apnea Among Atrial Fibrillation Patients: A Cross-Sectional Study from Jordan. Journal of Multidisciplinary Healthcare. 2024;17:701-10.
9. Szymański F, Platek A, Karpiński G, et al. Obstructive sleep apnoea in patients with atrial fibrillation: prevalence, determinants and clinical characteristics of patients in Polish population. Kardiol Pol 2014;72, 8:716–24.
10. Ben Halima M, Sammoud K, Ben Amar J, et al. Prevalence and predictors of Sleep Apnea in Atrial Fibrillation patients. Tunis Med. 2020;98(12):1031-8.