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Date Published: 09/04/2025
Abstract Views: 54
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DOI: https://doi.org/10.51298/vmj.v548i1.13472
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Vol. 548 No. 1 (2025)
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Các bài báo
How to Cite
Lê Hạ Long, H., Lê Mạnh, Q., Đại Diễm, Q., Nguyễn Kim, Đồng, Trần Tín, N., & Vũ Thị, H. (2025). THE PREVALENCE OF HUMAN PAPILLOMAVIRUS (HPV) INFECTION IN TONSILLAR CARCINOMA PATIENTS. Vietnam Medical Journal, 548(1). https://doi.org/10.51298/vmj.v548i1.13472

THE PREVALENCE OF HUMAN PAPILLOMAVIRUS (HPV) INFECTION IN TONSILLAR CARCINOMA PATIENTS

Hải Lê Hạ Long, Quân Lê Mạnh, Quỳnh Đại Diễm, Đồng Nguyễn Kim, Nghĩa Trần Tín, Hà Vũ Thị

Main Article Content

Abstract

Tonsillar carcinoma arises from the malignant transformation of the epithelial cells covering the tonsils or the connective tissues within the tonsil structure. Human papillomavirus (HPV) infection is associated with head and neck tumors, including tonsillar squamous cell carcinoma. Objectives: the prevalence of human papillomavirus (HPV) infection in patients with tonsillar squamous cell carcinoma at Hanoi Medical University Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 42 paraffin-embedded tissue samples from patients diagnosed with tonsillar squamous cell carcinoma at Hanoi Medical University Hospital during 2022. Semi-nested PCR amplification of the L1 gene of HPV DNA, and the sequencing method was HPV genotyped. Results and Conclusion: The average age of the patients in our study was 54.97±9.64 years, with those aged over 60 comprising the highest proportion (38.1%). Male patients constituted the majority (88.1%). The rate of HPV positivity in tonsillar squamous cell carcinoma patients was 23.8%, including HPV16 and HPV18 with 90% and 10.0%, respectively.

Article Details

Keywords

Tonsillar carcinoma, Human papillomavirus

References

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