SHORT-TERM PROGNOSTIC VALUE OF THE ACUTE HF SCORE IN HOSPITALIZED ACUTE HEART FAILURE PATIENTS

Hùng Trương Phi, Tài Nguyễn Nhật, Quang Nguyễn

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Abstract

Introduction: Acute heart failure (AHF) remains one of the leading causes of hospital admissions, with both short-term and long-term mortality rates remaining high after hospitalization. Therefore, risk stratification in hospitalized AHF patients is essential. The ACUTE HF score, which includes seven parameters, helps stratify the risk of AHF patients and provides a reliable prognosis for both short-term and long-term mortality. In Vietnam, there are currently few studies on the ACUTE HF score in hospitalized AHF patients. Objective: This study was conducted to evaluate the role of the ACUTE HF score in predicting short-term outcomes in hospitalized AHF patients. Subjects: Patients with acute heart failure admitted to Cho Ray Hospital from January 2024 to June 2024. Study design: A cross-sectional descriptive study with longitudinal follow-up. Results: A total of 129 patients meeting the inclusion criteria were enrolled. The median age of the study population was 66 years (IQR: 55–76), with a female predominance of 51.9%. The most common causes of heart failure were coronary artery disease (70.5%), valvular heart disease (12.4%), and hypertension (2.3%). The leading precipitating factors for AHF hospitalization were infections (50.4%), medication non-adherence (17.8%), and acute myocardial infarction (8.5%).. Based on the ACUTE HF score: Low-risk group (<1.5 points): 83 patients (64.3%), Intermediate-risk group (1.5–3 points): 41 patients (31.8%), High-risk group (>3 points): 5 patients (3.9%). The high-risk group had a significantly higher composite outcome of 30-day all-cause mortality and rehospitalization compared to the intermediate- and low-risk groups (p < 0.001). The ACUTE HF score demonstrated a fair predictive ability for 30-day mortality and rehospitalization, with an AUC of 0.71 (95% CI: 0.61–0.81). Conclusion: The ACUTE HF score has a fair predictive value for short-term outcomes in hospitalized AHF patients, with an AUC of 0.71.

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References

1. Shahim B, Kapelios CJ, Savarese G, Lund LH. Global Public Health Burden of Heart Failure: An Updated Review. Cardiac failure review. 2023; 9: e11. doi:10.15420/cfr.2023.05
2. Arrigo M, Jessup M, Mullens W, et al. Acute heart failure. Nature reviews Disease primers. Mar 5 2020;6(1):16. doi:10.1038/s41572-020-0151-7
3. Long B, Keim SM, Gottlieb M, Collins SP. What are the Data for Current Prognostic Tools Used to Determine the Risk of Short-Term Adverse Events in Patients with Acute Heart Failure? The Journal of Emergency Medicine. 2023/12/01/ 2023;65(6):e600-e613. doi:https:// doi.org/10.1016/j.jemermed.2023.05.026
4. Pastore MC, Mandoli GE, Campora A, et al. ACUTE HF score predicts in-hospital mortality in patients with acute heart failure. European Heart Journal. 2023;44(Supplement_2):ehad655.1100. doi:10.1093/eurheartj/ehad655.1100
5. Kaneko T, Kagiyama N, Nakamura Y, et al. External validation of the ACUTE HF score for risk stratification in acute heart failure. Int J Cardiol. Jan 1 2023;370:396-401. doi:10.1016/ j.ijcard.2022.10.130
6. Cameli M, Pastore MC, De Carli G, et al. ACUTE HF score, a multiparametric prognostic tool for acute heart failure: A real-life study. International Journal of Cardiology. 2019; 296:103-108. doi:10.1016/j.ijcard.2019.07.015
7. Feng J, Zhang Y, Zhang J. Epidemiology and Burden of Heart Failure in Asia. JACC: Asia. 2024/04/01 2024;4(4):249-264. doi:10.1016/j.jacasi.2024.01.013
8. Bezati S, Velliou M, Ventoulis I, Simitsis P, Parissis J, Polyzogopoulou E. Infection as an under-recognized precipitant of acute heart failure: prognostic and therapeutic implications. Heart failure reviews. Jul 2023;28(4):893-904. doi:10.1007/s10741-023-10303-8