RESULTS OF THORACOSCOPIC THYMECTOMY FOR MYASTHENIA GRAVIS IN HANOI MEDICAL UNIVERSITY HOSPITAL

Tú Võ Ngọc, Thắng Nguyễn Duy, Tùng Phạm Thanh, Gia Nguyễn Duy, Phương Nguyễn Thị

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Abstract

Objectives: To evaluate the results of thoracic endoscopic thymectomy for myasthenia gravis. Method: a cross-sectional descriptive research method for all the patients who were operated at Hanoi Medical University Hospital in the period of 2020-2022 using. Results: The study included a total of 26 patients, of which 69.2% were female, with an average age of 49.9±14.0 years (24-82 years old). At the time of admission, myasthenia gravis status according to Osserman and Genkins classification was: 19.2% grade 1, 57.7% grade IIA, 19.2% grade IIB and 3.8% grade III. Quantitative test for anti-acetylcholine receptor antibodies: <0.5 in 1 patient, accounting for 5.9%; ≥0.5 in 16 patients, accounting for 94.1%. Average surgical time was 68.3±33.4 minutes. The average postoperative hospital stay was 4.1±2.0 days and the complication rate were 1/26 patients with intercostal neuralgia, accounting for 3.8%. The average postoperative follow-up time was 16.8 months, 3.8% had complete recovery, 77.0% had symptom improvement and reduced treatment dose, and 19.2% had worsening symptoms. Conclusions: Thoracic endoscopic thymectomy for myasthenia gravis is a safe, highly effective, and aesthetic method, and is a combined treatment for myasthenia gravis.

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References

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