AXILLARY LYMPH NODE METASTASIS STATUS IN INVASIVE LOBULAR BREAST CANCER
Main Article Content
Abstract
Objective: To improve the quality of diagnosis, treatment, and prognosis for breast cancer in general and invasive lobular carcinoma (ILC) in particular. Subjects and Methods: We conducted a retrospective descriptive study on 167 ILC patients who underwent a mastectomy at K Hospital from January 2019 to July 2023. Results: The rate of axillary lymph node metastasis were 63.5%. The type accounted for the highest rate with the polymorphic, accounting for 82.9%. Several factors such as histological grades, hormone receptors, and tumor size are associated with axillary lymph node metastasis in ILC. Conclusion: Axillary lymph node metastasis in ILC is common; the larger the tumor, the higher the rate of lymph node metastasis. Axillary lymph node metastasis is also related to hormone receptor status and tumor grading.
Article Details
Keywords
breast cancer, axillary lymph node metastasis, invasive lobular carcinoma of the breast
References


2. Zengel B, Yararbas U, Duran A, et al. Comparison of the clinicopathological features of invasive ductal, invasive lobular, and mixed (invasive ductal + invasive lobular) carcinoma of the breast. Breast cancer (Tokyo, Japan). Jul 2015;22(4):374-81. doi:10.1007/ s12282- 013-0489-8


3. Danzinger S, Pöckl K, Kronawetter G, et al. Axillary lymph node status and invasive lobular breast cancer: Analysis of the Clinical Tumor Register of the AGO Austria. Wiener klinische Wochenschrift. Sep 2023;135(17-18):463-471. doi:10.1007/s00508-023-02162-y.


4. Ohashi R, Matsubara M, Watarai Y, et al. Pleomorphic lobular carcinoma of the breast: a comparison of cytopathological features with other lobular carcinoma variants. Cytopathology : official journal of the British Society for Clinical Cytology. Apr 2017;28(2):122-130. doi:10.1111/ cyt.12362


5. Iorfida M, Maiorano E, Orvieto E, et al. Invasive lobular breast cancer: subtípes and outcome. Breast Cancer Res Treat. Jun 2012;133(2): 713-23. doi:10.1007/s10549-012-2002-z.


6. Duraker N, Hot S, Akan A, Nayır P. A Comparison of the Clinicopathological Features, Metastasis Sites and Survival Outcomes of Invasive Lobular, Invasive Ductal and Mixed Invasive Ductal and Lobular Breast Carcinoma. European journal of breast health. Jan 2020;16(1):22-31. doi:10.5152/ejbh.2019.5004


7. Nguyễn Thị Quỳnh. Đặc điểm di căn hạch nách ung thư biểu mô tuyến vú thể đặc biệt. 2021.
