THE EFFECTIVENESS OF ERYTHROMYCINE IN THE TREATMENT OF PITYRIASIS ROSEA OF GIBERT

Huyền Trần Thị, Hằng Phạm Thị

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Abstract

This interventional study was conducted to evaluate the effectiveness of oral erythromycin in treating pityriasis rosea of Gibert on patients with moderate to severe. The study group received oral erythromycin at 250mg four times daily, divided into two doses and other medications for two weeks; the control group did not receive oral erythromycin. After 4 weeks of treatment, the mean Pruritus Numeric Rating Sacle (PNRS) of the erythromycin group was 1.7±1.3, while that of the control group was 1.6±1.4 (p=0.85). The mean Pityriasis Rosea Severity Score (PRSS) of the erythromycin group was 13.7±6.4, whereas that of the control group was 10.1±6.4 (p=0.03). The cure rate in the erythromycin group was 33.3%, higher than that in the control group (20%) but p>0.05. In the erythromycin group, there were 2 cases of adverse effects, with one case (3.3%) manifested in gastrointestinal symptoms (nausea, epigastric pain) and another case (3.3%) presenting with temporary skin rash. Erythromycin may be suitable for treating moderate to severe pityriasis rosea.

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References

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