SO SÁNH SUVMAX CỦA KHỐI U NGUYÊN PHÁT VỚI TỔN THƯƠNG DI CĂN TRÊN PET/CT Ở BỆNH NHÂN UNG THƯ PHỔI KHÔNG TẾ BÀO NHỎ

Abstract

Objective: To compare the SUVmax of primary tumor and metastasis lesions in NSCLC. Patient and method: Patients dignosed with non small cell lung cancer based on pathology results were retrospective analyzed at Oncology and Nuclear Medicine Department - Bach Mai Hospital, from November 2015 to October 2018. They were undergone 18F-FDG PET-CT scans before the treatment. The variables include: SUVmax of primary tumor, lung metastases, mediastinal lymph nodes, distant organ metastases. Results: SUVmax of primary tumor were 10.41 ± 3.82 and not different due to tumor location (p> 0.05). SUVmax was highest in liver and abdominal lymph node, respectively 7.53 ± 4.63 and 7.50 ± 3.15; the lowest SUVmax in lung metastases and hilar lymph nodes, respectively 4.41 ± 2.81 and 5.57 ± 2.46. SUVmax was significantly greater for primary tumor than that of regional metastases (mediastinal lymph nodes, hilar lymph nodes, and lung metastases) (p <0.01). SUVmax of the second primary tumor was significantly greater than that for pulmonary metastases (8.17 ± 2.65 vs. 4.41 ± 2.81, p <0.01). SUVmax of primary tumors are significantly greater than SUVmax of distant organ metastases (liver, bone, adrenal gland) (p <0.01). Conclusion: PET/CT is a very good image technique to diagnose NSCLC and differenciate to metastases. Thus, it takes an important part in stagging of NSCLC.