SOME REALTED FACTORS WITH FRAILTY SYNDROME IN ELDERLY DIABETIC PATIENTS WITH VERY HIGH CARDIOVASCULAR RISK FACTORS AT THE NATIONAL GERIATRIC HOSPITAL

Tâm Nguyễn Ngọc, Anh Nguyễn Trung

Main Article Content

Abstract

Objectives: To explore some related factors with frailty syndrome in elderly typ 2 diabetic with very high cardiovascular risk factors according to Edmonton Frail Scale (EFS). Subject and methods:  A cross- sectional study on patients with diabetes ≥ 60 years old with very high cardiovascular risk factors who came for examination and treatment at the National Geriatric Hospital. Subjects were diagnosed for Frailty syndrome using the EFS scale. Some related factors were assessed, including socialdemographic, diabetes, cardiovascular factors and geriatric syndromes. Result: A total of 289 older patients were recruited in the study. The rate of Frailty syndrome was 32,2 %. In multivariable logistic regressionHbA1c ≥ 7.5% (OR 3.0, 95%CI 1.1 – 8.0), multicomorbidity (OR 1.5, 95%CI: 1.1 – 2.2), dependence in activities daily living (ADL OR 3.3, 95%CI 1.5 – 7.1; IADL OR 3.3, 95%CI 1.5 – 7.9) and cognitive impairment (OR 5.4, 95%CI 2.4 – 11.9) were signitficantly associated with higher odd ratio of having frailty. Conclusion: Screening for Frailty syndrome is recommended for older diabetic patients having very high cardiovascular risk factors, especially for patients having uncontrolled diabetes, dependency, multicomorbidity and cognitive impairment.

Article Details

References

1. National diabetes statics report: estimates of diabetes and ít burden in the United State, 2014.
2. Marta Wleklik. Frailty Syndrome in Older Adults with Cardiovascular Diseases–What Do We Know and What Requires Further Research? https: //www.ncbi.nlm.nih.gov/pmc/articles/PMC8872246
3. Krentz AJ, Viljoen A, Sinclair AJ. Insulin resistance: a risk marker for disease and disability in the older person. Diabet Med https://pubmed. ncbi.nlm.nih.gov/23173973/
4. Matheus AS, Tannus LR, Cobas RA, Palma CC, Negrato CA, Gomes MB. Impact of diabetes on cardiovascular díeases: an update. Int Hypertent. 2013.
5. Assessment tools to evaluate Activities of Daily Living (ADL) and Instrumental Activities of Daily Living (IADL) in older adults: A systematic review. https://www. ncbi.nlm.nih.gov/pmc/articles/PMC7320974/
6. Concept: Charlson Comorbidity Index. http://mchpappserv.cpe.umanitoba.ca/viewConcept.php?printer=Y&conceptID=1098
7. Crum RM, Anthony JC, Bassett SS, Folstein MF. Population-Based Norms for the Mini- Mental State Examination by Age and Educational Level. JAMA. 1993;269(18):2386-2391. doi:10. 1001/jama.1993.0350018 0078038 %J JAMA
8. Nguyễn Xuân Thanh. Hội chứng dễ bị tổn thương và các yếu tố liên quan trên bệnh nhân cao tuổi điều trị tại BV Lão khoa TW. Luận văn thạc sĩ y học (2015) – Đại học Y Hà Nội
9. Vũ Thu Thủy, Nguyễn Xuân Thanh, Vũ Thị Thanh Huyền. Hội chứng dễ bị tổn thương và một số yếu tố liên quan ở người cao tuổi mắc đái tháo đường tại bệnh viện 19-8. Tạp chí Nội tiết và đái tháo đường số 66 năm 2023.
10. Daiki Watanabe, Tsukasa Yoshida, Yayu Watanabe. Frailty modifies the association of body mass index with mortality among older adults: Kyoto-Kameoka study https://www .sciencedirect.com/science/article/pii/S0261561424000025