MỐI LIÊN QUAN GIỮA THÔNG SỐ TRIGLYCERID GLUCOSE – CHỈ SỐ KHỐI CƠ THỂ VỚI TĂNG HUYẾT ÁP

Abstract

Background: Insulin resistance may have an impact on raised blood pressure through various potential mechanisms. Triglycerid glucose – body mass index (TyG-BMI) has been proposed an alternative marker of insulin resistance. This study aimed to explore the relationship between TyG-BMI index and hypertension. Methods: This cross-sectional study included 240 participants. The participants were divided into two groups: 120 individuals with new-onset hypertension and 120 healthy individuals, all from the Outpatient Department of the University Medical Center Ho Chi Minh City, during the period from August 2024 to November 2024. Results: The average age of the participants was 42.0 ± 8.2 years, and 68.3% of the participants in the hypertension group were male. The TyG-BMI index was significantly higher in the hypertensive group compared to the normotensive group, with a mean TyG-BMI of 239.2 ± 32.9 and 208.3 ± 18.4, respectively (p < 0.001). Logistic regression analysis revealed that the TyG-BMI index was strongly associated with hypertension, with an odds ratio (OR) of 4.79 (95% CI: 3.05 – 7.02, p < 0.001) for each standard deviation increase. Conclusion: The TyG-BMI index demonstrated a strong positive association with hypertension.