MỘT SỐ ĐẶC ĐIỂM LÂM SÀNG, MÔ BỆNH HỌC VÀ HÓA MÔ MIỄN DỊCH UNG THƯ BIỂU MÔ TIỂU THÙY XÂM NHẬP CỦA VÚ

Abstract

Objective: To improve the quality of diagnosis, treatment, and prognosis for breast cancer. Subjects and Methods: We conducted a retrospective descriptive study on 167 invasive lobular carcinoma (ILC) patients who underwent a mastectomy at K Hospital from January 2019 to July 2023. Results: The mean age of the study group was 52,78 ± 11,64 years. Mean tumor size was 2,81±1,51cm. In the study, the majority of patients with ILC were unifocal with 154 cases accounting for 92.2%; the rate of multifocal was 7.8%. ER-positive, PR-positive and HER2-positive rate were 88,0%, 79,0%, 12%, respectively; Ki67 more than 20% made up 45,5%. Luminal A and luminal B with HER2(-) subtypes accounted for the highest rate with 40,1% and 41,9% respectively. The Luminal B with HER2(+), HER2-enriched, Tripple negative breast cancer subtype accounted for a small percentage, there were 10 cases and equivalent to 6% for each of these 3 subtypes. Conclusion: The mean age of the group was 52,78 ± 11,64 years. Mean tumor size was 2,81±1,51cm. In the study, the majority of patients with ILC were unifocal accounting for 92.2%; the rate of multifocal was 7.8%. Luminal A and luminal B with HER2(-) were the two most common subtypes in ILC with the rate of 40,1% and 41,9% respectively.