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Date Published: 21/04/2025
Abstract Views: 27
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DOI: https://doi.org/10.51298/vmj.v548i3.13624
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Vol. 548 No. 3 (2025)
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Nguyễn Văn, Đăng, & Nguyễn Huy, P. (2025). RESULTS OF DEFINITIVE RADIATION THERAPY FOR HEAD AND NECK EXTRAMEDULLARY PLASMACYTOMA AT VIETNAM NATIONAL CANCER HOSPITAL. Vietnam Medical Journal, 548(3). https://doi.org/10.51298/vmj.v548i3.13624

RESULTS OF DEFINITIVE RADIATION THERAPY FOR HEAD AND NECK EXTRAMEDULLARY PLASMACYTOMA AT VIETNAM NATIONAL CANCER HOSPITAL

Đăng Nguyễn Văn, Phan Nguyễn Huy

Main Article Content

Abstract

Objective: To describe clinical, para-clinical features and treatment results of Extramedullary Plasmacytoma patients treated by definiteve radiation therapy at National Cancer Hospital from January 2018 to December 2024. Patients and Methods: A Retrospective Case series on 13 patients diagnosed with extramedullary plasmacytoma at National Cancer Hospital from January 2018 to December 2024. Results: The average age was 51.5 ± 16.3 years, with male-to-female ratio of 3.33/1. Nasal discharge and nosebleeds were the most common reason for hospital admisssion, accounting for 38.5% and 30.8%. Radiation dose was 40 to 56Gy in 1.8-2Gy per fraction; The overall response rate was 100%; complete response 84.6%. Acute side effects occurred in 4 patients (30.8%). After the follow-up, no cases of recurrence or progression were detected. Conclusion: definitive radiation therapy is an effective mordality to treat extramedullary plasmacytoma. However, studies with longer follow-up time and larger cohort are needed to accurately assess the effectiveness and toxicities of radiation therapy in EMP patients.

Article Details

Keywords

Extramedullary plasmacytoma, Definitive Radiation therapy

References

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