CLINICOPATHOLOGIC ANALYSIS OF STABLE VITILIGO
Main Article Content
Abstract
Objectives: To describe the clinical, histopathological, and immunohistochemical characteristics of stable vitiligo at the National Hospital of Dermatology and Venereology. Subjects and methods: A cross-sectional, prospective study of 65 patients with stable vitiligo (including 5 cases with histopathological and immunohistochemical results) conducted from December 2020 to December 2023. Results: Segmental vitiligo accounted for 83.08% of cases, with lesions mainly located on the face, accounting for 92.31%. Time of disease stability was 6.61 ± 6.66 years. 100% of patients had opaque white lesions with demarcated margin. None of the patients had trichrome vitiligo, confetti-like pattern or Kobner sign. Of the 5 patients with histopathological results, only 1 patient had the image of dermal melanophages. 1 patient had positive result for HMB-45 (3 cells at the field of view at 40x magnification). The average number of S-100 positive cells was 17.6 ± 4.62 cells. Conclusion: There is a close correlation between clinical signs and histopathological characteristics of stable vitiligo. There is no similarity between our study and other authors in the world when using HMB-45 and S-100 to evaluate the activity level of vitiligo.
Article Details
Keywords
Stable vitiligo, National Hospital of Dermatology and Venereology, HMB-45, S-100, non-cultured epidermal cell suspension
References

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