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COMPARISION THE CLINICAL, PARACLINICAL BETWEEN GRAM NEGATIVE AND GRAM POSITIVE SEPTICEMIA
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Abstract
Descriptive, cross-sectional study of 300 patients with blood stream infection treated at the National Hospital of Tropical Diseases from 2017 to 2022 to compare clinical and paraclinical characteristics of septicemia caused by Gram-positive and Gram-negative bacteria. Results: There were 124 cases (41.3%) with septicemia due to Gram-positive bacteria and 176 cases (58.7%) due to Gram-negative bacteria; 47 patients (15.6%) had septic shock, the mortality rate in the study was 17.3%. The rate of Gram-negative septicemia was significantly higher than the rate of Gram-positive septicemia among patients over 65 years old and among patients having the portal entry infection from gastrointestinal or urinary tract. By contrast, patients with skin and soft tissue portal entry infections had the rate of Gram-positive septicemia was greater than the rate of Gram-negative septicemia. The mean platelet count was significant lower, and the median procalcitonin level was significant higher in patients with Gram-negative septicemia than those with Gram-positive septicemia. There was no different in the rates of multiple organ failure, septic shock and death between the gram-negative and gram-positive septicemia groups. Conclusion: High incidence Gram-negative septicemia was found in people over 65 years old, and in people having portal entry infection from the gastrointestinal and urinary tract. Low platelet count and high procalcitonin level were the common factors in patients with Gram-negative septicemia.
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Keywords
Septicemia, gram-positive, gram-negative
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