ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG VÀ TÌNH TRẠNG DI CĂN HẠCH CỦA UNG THƯ TUYẾN GIÁP THỂ TỦY

Abstract

Objective: To evaluate the clinicopathological and nodal metastasis characteristics of medullary thyroid cancer. Subject and methods: retrospective combined with prospective cohort study of 34 medullary thyroid carcinoma patients treated by surgery at Hanoi Medical University Hospital from 1^st January 2015 to 30^th Jun 2020. Results: The mean age was 48.1 ± 11,2 and the ratio of female/male was 1.26/1. Most patients presented with an asymptomatic (55.9%). 76.5% of  tumors were classified as TIRADS 4 on ultrasound and FNA gave defined or suspicious for medullary thyroid cancer result in 55.9% of cases. All patients had undergone total thyroidectomy and neck dissection. The overall rate of nodal metastasis was 47.1%. Central neck compartment nodal metastasis only was detected in 31.2% cases, while 62.5% of patients had positive nodes in both central and lateral neck. The occult nodal metastasis rate was 21.1%. The analysis showed that the nodal metastasis was significantly related with the male sex (p<0.05). Conclusion: MTC are difficulty diagnosed in clinique, cervical lymph node metastasis rate is high.