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Date Published: 16/12/2021
Abstract Views: 510
Views PDF: 270
DOI: https://doi.org/10.51298/vmj.v507i1.1370
Issue
Vol. 507 No. 1 (2021)
Section
Các bài báo
How to Cite
Thị Thu Hương, T. ., & Văn Liệu, N. . (2021). THE STUDY SOME CLINICAL CHARACTERISTICS AND MUTATION IN EARLY-ONSET PARKINSON PATIENTS. Vietnam Medical Journal, 507(1). https://doi.org/10.51298/vmj.v507i1.1370

THE STUDY SOME CLINICAL CHARACTERISTICS AND MUTATION IN EARLY-ONSET PARKINSON PATIENTS

Tô Thị Thu Hương1,, Nguyễn Văn Liệu1
1 Hanoi Medical University

Main Article Content

Abstract

Background: Studies about Parkinson have recently become a key topic among neurodegenerative status research. The disease was ranked at the second highest prevalence accounting for 1.6% of all neurological diseases In Parkinson's disease, an autosomal recessive gene mutation can increase a young person's risk of Parkinson's, even if only one copy of the mutated gene is inherited. Objectives: Describe some clinical features of patients with early-onset Parkinson's disease and describe some mutations in patients with early-onset Parkinson's disease. Methods: This is a cross-sectional study conducted among 30 Parkinson patients who were initially diagnosed with primary Parkinson, based on criteria for Parkinson diagnosis of the Brain bank of the Parkinson Disease Society in the United Kingdom, at the age of less than 50 years old in the National Geriatric hospital, Bach Mai hospital. Results: The mean age of onset was 41 with a male:female ratio of 1.9. The symptom of tremor at rest was the most common with the rate of 93.8%. And the most common gene mutation is GBA

Article Details

Keywords

Parkinson, mutation, early-onset parkinsonism

References

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