NGHIÊN CỨU TRỊ SỐ SUV MAX CỦA HẠCH DI CĂN TỪ UNG THƯ PHỔI BIỂU MÔ TUYẾN TRÊN PET/CT

Abstract

Background: Lung cancer is a fairly common malignant disease of the respiratory system. Lung cancer if detected late, very poor prognosis, very high mortality and death in a short time since the detection of the disease. PET / CT in the diagnosis and assessment of non-small cell lung cancer stage, especially lung carcinoma, is increasingly confirmed. Objective: To investigate the SUV max of medial node in epithelial lung carcinoma on PET / CT. Patients and Methods: Patients diagnosed with epithelial lung carcinoma were identified by histopathology (biopsy, surgery). Research design: Retrospective study. Materials: PET / CT Biograph True Point - Siemens - Germany. CT scan with parameters of 80mA, 140KV, rotation speed of 0.5s / tube, thickness of 4.25mm, scan length of 867mm and time of data acquisition is 22.5s. Radioactive was F-18 FDG (2-fluoro-2-deoxy-D-glucose) at dosage 0.15-0.20 mCi / kg body weight (7-12mCi) intravenously. PET/CT was performed after injection of F-18 FDG 45-60 minutes. Results: 24 patients with epithelial lung carcinoma (16 males and 8 females), the lowest age was 34, the highest age was 74, the average was 58.1 ± 8.1 years. The high percentage of the lower lymph nodes (14.3%), the adjacent lymph node, left lung umbilical cord, upper lymph node (11.9% for each group). The median lymph node diameter is 2.1 ± 1.1 cm. The lowest SUV max is 3 (cm); largest 14.6 (cm); average 6.5 ± 3.3 (cm). The SUV max were positively correlated with medial lobe diameter (r = 0.651; p <0.01). Conclusion: The determination of SUV max of mediastinal lympho node is very valuable in the diagnosis of epithelial lung carcinoma, which contributes to treatment orientation and postmortem follow-up.