ACUTE KIDNEY INJURY IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY
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Abstract
Background: Acute kidney injury is a significant extracranial complication in patients with severe traumatic brain injury, contributing to increased mortality and prolonged hospital stays. However, data on the incidence and risk factors of acute kidney injury in severe traumatic brain injury patients in Vietnam remain limited. Objective: To determine the incidence and risk factors of acute kidney injury in patients with severe traumatic brain injury. Methods: A retrospective cohort study was conducted on severe traumatic brain injury patients (AIS ≥ 3) admitted to the Neurosurgical Intensive Care Unit of Chợ Rẫy Hospital from July 2023 to July 2024. Results: The incidence of acute kidney injury in severe traumatic brain injury patients within the first seven days was 8.3%. Among acute kidney injury cases, 35.7% were classified as stage 1, 35.7% as stage 2, and 28.6% as stage 3 according to KDIGO criteria. Independent risk factors for acute kidney injury included advanced age, severe extracranial injuries and RDW values. Patients who developed acute kidney injury had a significantly higher in-hospital mortality rate compared to those without acute kidney injury (57.1% vs. 26.0%, p = 0.026). Conclusion: Acute kidney injury occurs in 8.3% of severe traumatic brain injury patients and is strongly associated with older age, severe extracranial injuries and RDW values.
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Keywords
tổn thương thận cấp, chấn thương sọ não nặng
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