SEVERAL ASSOCIATED FACTORS TO DEPRESSIVE DISORDER IN PATIENTS WITH GENERALIZED EPILEPSY

Đỗ Quang Vinh1,, Nguyễn Văn Tuấn1
1 Hanoi Medical University

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Abstract

Background: Depressive disorder is a common disease in generalized epilepsy patients, which greatly affects the patient's quality of life, so early detection is extremely important. Many factors are thought to increase the prevalence of depressive disorder in patients with generalized epilepsy, such as the patient's age, marital status, and seizure frequency. Objectives: evaluate some associated factors  with depressive disorder in patients with generalized epilepsy. Method: A cross-sectional study on 53 patients with depressive disorder in 243 outpatients diagnosed with generalized epilepsy, treated at Hanoi Mental Hospital and Medical Center of Dong Anh town, from September 2020 to July 2021, using the Hamilton-D depression rating scale (Ham-D).. Results: Among 243 generalized epilepsy patients, 53 patients had depressive disorder (21,81%). Some associated factors increase the risk of depressive disorder in the study: age>40 (OR=2.875, p<0.001), single marital status (OR=2.039, p=0.046), age of onset (OR= 2.763, p=0.009), frequency of seizure > 1 seizure/month (OR=9.612, p<0.001), poly-therapy (OR=4,097, p<0.001). 

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References

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