CLINICAL, LABORATORY FEATURES, AND TREATMENT OUTCOMES OF STRONGYLOIDIASIS STERCORALIS INFECTION AT 108 MILITARY CENTRAL HOSPITAL

Kỳ Doãn Thái, Quang Phạm Minh Ngọc, Tuyết Dương Thị

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Abstract

Objective: To describe the clinical and laboratory characteristics of Strongyloides stercoralis infection and evaluate treatment outcomes in patients at 108 Military Central Hospital. Methods: A retrospective observational study was conducted on patients diagnosed with strongyloidiasis at 108 Military Central Hospital from January 2022 to October 2024. Data were collected on clinical presentation, laboratory findings, diagnostic methods, and treatment responses.. Results: A total of 28 patients were included in the study. The male-to-female ratio was 6:1. The most common risk factor was the use of immunosuppressive drugs (53.6%). Gastrointestinal symptoms included poor appetite, bowel disorders, weight loss, vomiting, and abdominal pain. Extra-gastrointestinal manifestations, such as skin rash and urticaria, were observed in 32.1% of patients. Diagnostic methods included stool microscopy (57.1% positive), anti-Strongyloides antibody detection (32.1%), and duodenal biopsy (42.9%). All patients were treated with ivermectin, with 25 out of 28 showing significant clinical improvement or cure. Conclusion: Strongyloides stercoralis infection should be considered in high-risk individuals, especially those receiving immunosuppressive therapy. Early detection and appropriate treatment with ivermectin result in favorable clinical outcomes.

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References

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