RESEARCH ON CLINICAL, PARA-CLINICAL FEATURES, SOME RELATED FACTORSA ON PATIENTS WITH HYPOKALEMIC PERIODIC PARALYSIS AT CAN THO CENTRAL GENERAL HOSPITAL FROM 2023 TO 2025
Main Article Content
Abstract
Background: Hypokalemic periodic paralysis is a myopathy in the group of ion channelopathies in the skeletal muscle cell membrane that causes intermittent generalized/localized flaccid paralysis with diverse clinical manifestations, making diagnosis and treatment difficult Objective: Describe clinical and paraclinical characteristics and determine the rate of some related factors and evaluate the treatment results of patients with periodic paralysis due to hypokalemia. Research method: The study carried out a cross-sectional descriptive research method on 43 patients diagnosed and treated at Can Tho Central General Hospital. Results: Clinical: Hypokalemic periodic paralysis (67.4%), paraplegia (60.5%), muscle strength 2/5 (27.9%), normal tendon reflexes (72.9%), severe hypokalemia at admission (60.47%). A meal rich in carbohydrates and physical activity before the attack were related factors. Conclusion: The clinical form of hypokalemic periodic paralysis is the most common. The most common clinical manifestation is paraplegia, with severe muscle paralysis and preserved tendon reflexes. Patients were admitted to the hospital mainly with severe hypokalemia. A meal rich in carbohydrates and physical activity may be involved in the onset of the attack.
Article Details
Keywords
Hypokalemic periodic paralysis, myopathy, flaccid paralysis
References

2. A. K. Kayal, M. Goswami, M. Das, R. Jain (2013), "Clinical and biochemical spectrum of hypokalemic paralysis in North: East India", Ann Indian Acad Neurol, 16(2), pp. 211-7.

3. U. Farooque, A. Y. Cheema, R. Kumar, et al (2020), "Primary Periodic Paralyses: A Review of Etiologies and Their Pathogeneses", Cureus, 12(8), pp. e10112.

4. Q. Z. Iqbal, M. Niazi, Z. Zia, S. B. A. Sattar (2020), "A Literature Review on Thyrotoxic Periodic Paralysis", Cureus, 12(8), pp. e10108.

5. P. Phuyal, B. S. Bhutta, S. Nagalli (2025), "Hypokalemic Periodic Paralysis", StatPearls, StatPearls Publishing Copyright © 2025, StatPearls Publishing LLC., Treasure Island (FL).

6. Đào Xuân Hải (2016), "Nghiên cứu đặc điểm lâm sàng, cận lâm sàng và các nguyên nhân thường gặp gây hạ kali máu có liệt chi", Trường Đại học Y Hà Nội, Hà Nội.

7. Bùi Minh Quang (2022), "Nghiên cứu đặc điểm lâm sàng, cận lâm sàng, các yếu tố nguy cơ, phả hệ và đánh giá kết quả điều trị của bệnh liệt chu kỳ hạ kali máu tại Bệnh viện Đa khoa Trung Ương Cần Thơ năm 2019-2022", Trường Đại học Y Dược Cần Thơ, Luận văn chuyên khoa cấp II.
