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Date Published: 16/12/2021
Abstract Views: 293
Views PDF: 210
DOI: https://doi.org/10.51298/vmj.v507i1.1382
Issue
Vol. 507 No. 1 (2021)
Section
Các bài báo
How to Cite
Văn Tân, T. ., & Ngọc Sơn, Đỗ . (2021). EFFECTIVENESS OF INTRAPULMONARY PERCUSSIVE VENTILATION IN THE TREATMENT OF PATIENTS WITH MILD TO MODERATE EXACERBATION OF CHRONIC PULMONARY OBSTRUCTIVE DISEASE. Vietnam Medical Journal, 507(1). https://doi.org/10.51298/vmj.v507i1.1382

EFFECTIVENESS OF INTRAPULMONARY PERCUSSIVE VENTILATION IN THE TREATMENT OF PATIENTS WITH MILD TO MODERATE EXACERBATION OF CHRONIC PULMONARY OBSTRUCTIVE DISEASE

Trần Văn Tân1, Đỗ Ngọc Sơn2,
1 Viet Tiep Hospital, Haiphong
2 Emergency Department, Bach Mai Hospital

Main Article Content

Abstract

Objective: To evaluate the effectiveness of intrapulmonary percussive ventilation (IPV) in the treatment of mild to moderate exacerbations of COPD patients. Methods: Prospective interventional study on 60 patients with acute exacerbation of COPD according to Anthonisen 1987, admitted to the Center for Emergency Medicine of Bach Mai Hospital from July  2020 to July 2021, of which 30 were assigned to standard treatment, and 30 to IPV. The main variables such as age, sex, vital signs parameters: heart rate, respiratory rate, saturation of peripheral oxygen (SpO2) at the time of admission (T0), 1 hour (T1), 6 hours (T2), 12 hours  hours(T3), 24 hours (T4), 48 hours (T5), 72h hours (T6) after IPV ; arterial blood gas indices such as pH, PaCO2, PaO2, HCO3- at the time of T0, T2, T4, T5, T6. The therapy was considered successful when non-invasive ventilation was avoided. Results: The study on 60 patients (mean age 69.83±9.90 years; 11.7% women), there were 6 (20%) patients in standard group who required NIV versus 1 (3.3%) patient in IPV group required NIV (p<0.05). The hospital stay of control group was 8.00 ± 2.95 days, of IPV group was 6.73 ± 2.99 days (p=0.105). There were 63.3% patients rated IPV as comfortable (Level I), 26.7% rated as mildly uncomfortable, however, there was no one withhold IPV. Conclusions: IPV is a safe technique and may prevent further deterioration in patients with acute axacerbations of COPD, reducing the  need for NIV.

Article Details

Keywords

Intrapulmonary percussive ventilation (IPV), Non-invasive mechanical ventilation (NIV), Exacerbations of chronic obstructive pulmonary disease (ECOPD)

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