NGUYÊN NHÂN PHẢN VỆ VÀ ĐẶC ĐIỂM LÂM SÀNG THEO NGUYÊN NHÂN Ở TRẺ EM TẠI BỆNH VIỆN NHI TRUNG ƯƠNG (2017-2021)

Abstract

Objectives: Trigger of anaphylaxis and characteristic symptoms for each trigger in children at Vietnam National Children’s Hospital. Method: A cross-sectional descriptive study was recorded 129 patients at Vietnam National Children’s Hospital from January 2017 to July 2021. Results: 63,6% of the participants are under 12 months old. The ratio of boy-girl is 1.4/1; 64.3% of patients were transferred from medical facilities. Drugs are the most common trigger of anaphylaxis 62.8%, vaccines: 18,6%, food: 14%, insect venom: 3,9%, others: 0,7%. The symptoms are diversity: drugs anaphylactic reactions affect the circulation (91%) and nerve system (88%), vaccine anaphylactic reactions affect the circulation (92%) and nerve system (96%); food and insect venom anaphylactic reactions affects the skin and mucous membranes (100%, 100%). Drugs and vaccines occur more Grade 3 anaphylaxis (64,2%; 54,2%) and are able to occur Grade 4 anaphylaxis (12,3%; 8,3%). Conclusions: Medication is the most common trigger of anaphylaxis. Drugs and vaccines anaphylaxis affects most on the circulation and nerve system. Food and insect venom anaphylaxis affects most on mucous membranes.