PAIN AND SKIN REACTION CHARACTERISTICS AMONG CANCER PATIENTS WITH RADIATION THERAPY AT 19-8 HOSPITAL AND SEVERAL ASSOCIATED FACTORS

Triệu Thị Minh1,2,, Trương Quang Trung2
1 19-8 Hospital, Ministry of Public Security
2 Hanoi Medical University

Main Article Content

Abstract

Prospective study has been conducted among cancer with radiation therapy at 19-8 Hospital to (1) describle pain and skin reaction characteristics among study participants and (2) explore several associated factors on skin reaction characteristics. 264 patients had been evaluated and monitored during 2020 – 2021. Result: 70.8% of cancer patient with radiation therapy had skind reaction as level 1 – 2 by RTOG and few patient wtih levels 3 of RTOG. Common skind symptoms include redness, itching, and burning. Symptoms often appear on the skin such as a feeling of warmth, burning accounting for 33.3%; itching and discomfort on the skin accounted for 27.1%; pain / stinging like needles on the skin accounted for 20.5%. Pain symptoms of cancer patients during radiation therapy were reported in 64.3%. The group of patients with treatment time over 20 days, radiation dose above 41 Gy, had a higher relative risk of skin reaction from 1.2 to 1.7 times higher than the other group of patients. Conclusion: It is necessary to focus of caring and monitoring early skin lesions in the group of patients with high and prolonged exposure time.

Article Details

References

1. Brown KR, Rzucidlo E. Acute and chronic radiation injury. Elsevier; 2011.
2. Williams PA, Cao S, Yang D, Jennelle RL. Patient-reported outcomes of the relative severity of side effects from cancer radiotherapy. Supportive Care in Cancer. 2020;28(1):309-316.
3. Wilkie JR, Mierzwa ML, Yao J, et al. Big data analysis of associations between patient reported outcomes, observer reported toxicities, and overall quality of life in head and neck cancer patients treated with radiation therapy. Radiotherapy and Oncology. 2019;137:167-174.
4. Ryan JL. Ionizing radiation: the good, the bad, and the ugly. Journal of Investigative Dermatology. 2012;132(3):985-993.
5. Lwanga SK, Lemeshow, Stanley & World Health Organization. Sample size determination in health studies : a practical manual / S. K. Lwanga and S. Lemeshow. World Health Organization. Accessed 20/6, 2021. https://apps.who.int/ iris/handle/10665/40062
6. Mannix CM, Bartholomay MM, Doherty CS, Lewis M, Bilodeau M-LC. A feasibility study of low-cost, self-administered skin care interventions in patients with head and neck cancer receiving chemoradiation. Clinical journal of oncology nursing. 2012;16(3)
7. Gewandter JS, Walker J, Heckler CE, Morrow GR, Ryan JL. Characterization of skin reactions and pain reported by patients receiving radiation therapy for cancer at different sites. The journal of supportive oncology. 2013;11(4):183.
8. Cox JD. Toxicity criteria of the radiation therapy oncology group (RTOG) and the European organization for research and treatment of cancer (EORTC). Int J Radiat Oncol Biol Phys. 1995;31:1341-1346.