RESULTS OF ULTRASOUND – GUIDED BIOPSY OF SYNOVIAL OF HIP JOINT

Bình Nguyễn Thái, Linh Trần Thị

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Abstract

This study was conducted to evaluate the safety and result of ultrasound-guided synovial biopsy in the diagnosis of hip joint diseases. The study was conducted on 27 patients with hip synovial abnormalities on ultrasound (US) and magnetic resonance imaging (MRI), who underwent biopsy at Hanoi Medical University Hospital from July 2020 to February 2025. The obtained specimens were analyzed for histopathology, bacterial culture, and tuberculosis PCR testing to accurately determine the cause of the lesions. The results showed that the group of patients over 50 years old was dominant (70.4%), with an average age of 56.44 ± 15.26. The success rate in sampling was 92.6%. Complications occurred in 14.8% of patients, including mild bleeding at the needle puncture site, with no serious complications. Histopathologically, 74.1% of patients were diagnosed with chronic inflammation, 7.4% with granulomatous inflammation specific to tuberculosis, 11.1% with septic arthritis, and 3.7% with synovial tumors. Overall, the study showed that US-guided synovial biopsy is a safe, minimally invasive, and highly accurate method in diagnosing synovial pathology of hip joint.

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References

1. Gerlag DM, Tak PP. How useful are synovial biopsies for the diagnosis of rheumatic diseases? Nat Rev Rheumatol. 2007;3(5):248-249. doi:10.1038/ncprheum0485
2. Pitzalis C, Kelly S, Humby F. New learnings on the pathophysiology of RA from synovial biopsies. Current Opinion in Rheumatology. 2013;25(3): 334-344.
3. Polido-Pereira J. Ultrasound-Guided Biopsies: Medium and Large Joints. Front Med. 2019;6:95. doi:10.3389/fmed.2019.00095
4. Sitt J, Griffith JF, Lai FM, et al. Ultrasound-guided synovial Tru-cut biopsy: indications, technique, and outcome in 111 cases. European radiology. 2017;27(5):2002-2010.
5. Kelly S, Humby F, Filer A, et al. Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients. Annals of the rheumatic diseases. 2015;74(3):611-617.
6. Koski JM, Helle M. Ultrasound guided synovial biopsy using portal and forceps. Annals of the rheumatic diseases. 2005;64(6):926-929.
7. Humby F, Romão VC, Manzo A, et al. A multicenter retrospective analysis evaluating performance of synovial biopsy techniques in patients with inflammatory arthritis: arthroscopic versus ultrasound‐guided versus blind needle biopsy. Arthritis & Rheumatology. 2018;70(5): 702-710.
8. Hung EHY, Griffith JF, Ng AWH, Lee RKL, Lau DTY, Leung JCS. Ultrasound of musculoskeletal soft-tissue tumors superficial to the investing fascia. AJR Am J Roentgenol. 2014; 202(6): W532-540. doi:10.2214/AJR.13. 11457