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Date Published: 05/05/2025
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DOI: https://doi.org/10.51298/vmj.v549i3.13943
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Vol. 549 No. 3 (2025)
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Thái Doãn, K., Đinh Thị, N., & Nguyễn Tiến, T. . (2025). APPLICATION OF ULCERATIVE COLITIS ENDOSCOPIC INDEX OF SEVERITY (UCEIS) SCORE IN ASSESSING THE SEVERITY OF ULCERATIVE COLITIS. Vietnam Medical Journal, 549(3). https://doi.org/10.51298/vmj.v549i3.13943

APPLICATION OF ULCERATIVE COLITIS ENDOSCOPIC INDEX OF SEVERITY (UCEIS) SCORE IN ASSESSING THE SEVERITY OF ULCERATIVE COLITIS

Kỳ Thái Doãn, Ngà Đinh Thị, Thắng Nguyễn Tiến

Main Article Content

Abstract

Objective: To evaluate the severity of ulcerative colitis (UC) patients using the Ulcerative Colitis Endoscopic Index of Severity (UCEIS). Methods: A cross-sectional descriptive study was conducted among 35 UC patients at 108 Central Military Hospital and 103 Military Hospital from May 2023 to May 2024. Results: The mean age of the study group was 48.6 ± 12.0 years. The majority (80%) of patients were aged between 30 and 60 years. The male-to-female ratio was 1.5:1. Based on the UCEIS score, 8.6% of patients had mild disease, 37.1% had moderate disease, and 54.3% had severe disease. UCEIS showed a positive correlation with C-reactive protein (CRP) levels (r=0.44, p=0.008) and a strong positive correlation with the Mayo endoscopic score (r=0.76, p<0.001). UCEIS demonstrated a stronger positive correlation with the Truelove-Witt score (r=0.47, p=0.005) compared to the correlation between the Mayo endoscopic score and the Truelove-Witt score (r=0.35, p=0.04).  Conclusion: The UCEIS is a reliable endoscopic index for assessing the severity of ulcerative colitis and demonstrates strong correlations with both the Mayo endoscopic score and the Truelove-Witt score.

Article Details

Keywords

Ulcerative Colitis, UCEIS, Mayo ES

References

1. Hiroshi Nakase et al. Evidence-based clinical practice guidelines for inflammatory bowel disease 2020 J Gastroenterol (2021) 56:489–526.
2. Lewis et al (2009). Use of the Non-invasive Components of the Mayo Score to Assess Clinical Response in Ulcerative Colitis Inflamm Bowel Dis. 14(12)
3. S. Travis et al. The Impact of Clinical Information on the Assessment of Endoscopic Activity: Characteristics of the Ulcerative Colitis Endoscopic Index Of Severity [UCEIS]. Journal of Crohn's and Colitis, 2015, 607–616
4. Siew C.Ng. et al. Incidence and phenotype of inflammatory bowel disease based on results from Asia- Pacific Crohn and Colitis Epidemiology study. Gastroenterogy. 2013;145:158–165.
5. Guideline on the development of new medicinal products for the treatment of Ulcerative Colitis CHMP/EWP/18463/2006 Rev.1
6. Rogler et al. (2021). Extraintestinal manifestions of IBD. Gastroenterogy. Vol 141. No 4.
7. Đinh Thị Ngà (2023). Biểu hiện lâm sàng ngoài ruột và tại ruột của bệnh nhân viêm ruột mạn tại Bệnh viện Trung ương quân đội 108. Tạp chí y dược lâm sàng 108, 18(3), 96-101.
8. Truelove SC, Witts LJ. Cortisone in ulcerative colitis; final report on a therapeutic trial. BMJ 1955; 2: 1041–48.
9. Satsangi, Silverberg, Vermeire, et al. The Montreal classification of inflammatory bowel disease: controversies, consensus, and implications. Gut 2006;55:749–753
10. Zhang X. F., Li P., Ding X. L., et al (2021). Comparing the clinical application values of the Degree of Ulcerative Colitis Burden of Luminal Inflammation (DUBLIN) score and Ulcerative Colitis Endoscopic Index of Severity (UCEIS) in patients with ulcerative colitis, Gastroenterol Rep (Oxf), 9(6), 533–542