THE RESULT OF BEVACIZUMAB (AVASTIN) INTRAOCULAR INJECTION ON RETINAL VEIN OCCLUSION MACULAR EDEMA

Trung Lê Quang, Sơn Cung Hồng, Thành Trần Ngọc

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Abstract

The clinical trial without control was carried out on 36 patients with intraocular injection in retinal vein occlusion macular edema. Injections of 1.25 mg of bevacizumab with 1 month interval were done for patients. Results: The median age was 65 years. There were 13 cases of  branch vein occlusion and 23 cases of central retinal vein occlusion. There were 10 cases of ischemic type and 26 cases of non-ischemic type. Cytoid macular edema (69,4%), diffuse edema (30,6%).  LogMAR VA before treatment was low 1.24±0,60. Good improvement of VA after treatment (1.24 - 0.81). Pretreatment central retinal thickness (CRT) was 542 ± 181 pm, which was improved remarkably after the intervention (542 - 336 µm). There was no close correlation between the CRT reduction and VA improvement throughout all follow-up points. There was no reported considerable systemic complications neither ocular adverse effects. Avastin intraocular injections appeared to be a safe and effective treatment for RVO macular edema.

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References

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