TỈ LỆ ĐỀ KHÁNG KHÁNG SINH CỦA VI KHUẨN ENTEROBACTERIACEAE TẠI KHOA NGOẠI BỆNH VIỆN ĐA KHOA TỈNH TRÀ VINH NĂM 2024

Abstract

Background: The Enterobacteriaceae family is one of three bacterial families with antibiotic resistance rates that are among the most dangerous, making it difficult to choose antibiotics, leading to inappropriate antibiotic use that promotes the development of drug resistance, leading to prolonged hospital stays, increased treatment costs, causing significant economic impacts on individuals, families, and society, and also causing a high risk of death. Objective: Determining the antibiotic resistance rate of bacteria belonging to the Enterobacteriaceae family at the Department of Surgery, Tra Vinh Provincial General Hospital in 2024. Materials and methods: Descriptive cross-sectional study design, 115 isolated bacteria were included in the study to analyze antibiotic resistance. Bacterial strains were identified and performed antibiotic susceptibility testing using the WalkAway 96 plus system. Results: E. coli has a high resistance rate of over 80% to the antibiotics ampicillin, piperacillin, ciprofloxacin, cefazolin, levofloxacin; Klebsiella spp. has a high resistance rate of over 70% to the antibiotics ampicillin, ciprofloxacin, levofloxacin, cefazolin; Enterobacter spp. has a high resistance rate of over 80% to the antibiotics ampicillin, cefoxitin, cefuroxime, cefazolin, ampicillin-sulbactam, cefuroxime. Conclusion: Most intestinal bacterial strains are highly resistant to antibiotics such as ampicillin, first-, second-, and third-generation cephalosporins, and quinolones, but are still sensitive to tigecycline, amikacin, piperacillin-tazobactam, and carbapenems (imipenem, meropenem, doripenem).