FACTORS THAT INFLUENCE THE OCCURRENCE OF MULTIPLE PREGNANCIES AFTER FROZEN EMBRYO TRANSFER ON DAY 3

Trần Thị Phương Hoa1,, Nguyễn Mạnh Hà1
1 Center of IVF, Hanoi Medical University Hospital

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Abstract

Multiple pregnancies are an important complication of In Vitro Fertilization (IVF). This study aims to indentify the related factors for multiple pregnancies after frozen embryo transfers on day 3. This retrospective study carred out on 112 patients who underwent intracytoplasmic sperm injection (IVF/ICSI) cycles in Center of IVF and Tissue engineering, Hanoi Medical University Hospital between January 2018 and December 2020. Factors were obtained from two groups: cycles with double frozen embryos transfer  and cycles that transferred three frozen embryos. These factors were entered into multivariable logistic regression to identify related factors for multiple pregnancies. The results showed that, in 112 patients with at least 1 gestational sac after embryo transfer, the rate of multiple pregnancies accounted for 36%. The incidence of multiple pregnancy in the group of three embryos transfer was 1.685 times higher than that of the double embryos transfer group. Maternal age and quality of transfered embryo also affect the number of gestational sacs of the patient, the rate of multiple pregnancies increased in the younger age group (37.4% in the group < 35 years old and 28.6% in the group ≥ 35 years old), the incidence of multiple pregnancy in the group with only 1 embryo of grade 1 or 2 decreased 0.654 times than the group with both embryos of grade 1 and 2.

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References

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