ĐẶC ĐIỂM LÂM SÀNG, CẬN LÂM SÀNG, KẾT QUẢ ĐIỀU TRỊ NHIỄM GIUN LƯƠN Ở BỆNH VIỆN ĐẠI HỌC Y HÀ NỘI

Abstract

Introduction: Strongyloidiasis is a neglected tropical parasitic disease that affects a significant portion of the global population, particularly in developing countries. The disease can lead to severe complications and mortality if diagnosed late; therefore, increasing awareness and understanding of the disease is essential for timely diagnosis and treatment. Subjects and Methods: A cross-sectional descriptive study, combining retrospective and prospective analysis, was conducted on 40 patients with gastrointestinal strongyloidiasis at Hanoi Medical University Hospital from January 2021 to September 2023. Patients were selected using a convenience sampling method, including all eligible patients diagnosed with strongyloidiasis during the study period. Results: The disease primarily affects older adults (mean age 63.2 years) and is often associated with underlying conditions or immunosuppression. Common symptoms included abdominal pain (65%), diarrhea (47.5%), and nausea/vomiting (35%). Laboratory findings frequently showed eosinophilia (72.5%), hypoalbuminemia (72.5%), and anemia (67.5%). Diagnosis was based on ELISA testing (95% positive) and the detection of larvae in stool samples (37.5%). Treatment with a regimen of ivermectin and albendazole effectively improved symptoms and laboratory markers without significant side effects, with a 100% patient response rate.