ADAPTIVE VENTILATION MODE FOR WEANING ON PATIENTS WITH THE EXACERBATION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE

Nguyễn Đức Lịch1,, Đỗ Ngọc Sơn2
1 Phu Tho General Hospital
2 Bach Mai Hospital

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Abstract

Objective: To evaluate of weaning results of adaptive ventilation mode (AVM) for patients with the  exacerbation of chronic obstructive pulmonary disease (COPD). Methods: A prospective, on 25 invasive ventilated patients due to COPD exacerbations admitted to the Center for Emergency Medicine of Bach Mai Hospital from September 2020 to August 2021. The main variables such as age, sex, blood gas indices: pH, PaCO2, PaO2, HCO3, PaO2/FiO2 ratio, lactate, vital signs parameters: heart rate, blood pressure, respiratory rate , SpO2 were collected at the timelines: admission, 30 minutes, 60 minutes, 120 minutes after AVM, before extubation and after extubation. Patients were considered as successful weaning if they were not  be re-intubated after 48 hours. Results: Among 25 patients (mean age 74.04 ± 9.92 years; 8% women), there were 21 (84%) patients with successful extubated. In the successful extubation group, weaning time (9,06 ± 4,5 hours) and ICU length of stay (6.29 ± 2.61 days), shorter than those of failure group (16.75 ± 5.38 hours), (20.75±27.58), with p<0.05, respectively.  Conclusion: The AVM has a higher rate of successful extubation and shorter duration of mechanical ventilation and  shorter ICU LOS in patients with exacerbation of chronic obstructive pulmonary disease (COPD).

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References

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