EFFECT OF 1450-PPM FLUORIDE TOOTHPASTES ON THE ENAMEL REMINERALIZATION: AN IN-VITRO STUDY
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Abstract
Objectives: This study aimed to evaluate the remineralization efficacy of toothpaste containing 1450ppm fluoride by assesing enamel surface hardness in in-vitro. Subjects and methods: The study subjects consisted of 36 enamel samples taken from extracted permanent third molars (n = 36). The enamel samples were initially demineralized to simulate early-stage caries lesions, then randomly divided into three groups and subjected to a pH cycling remineralization process for 14 days. Each group (12 teeth) was treated with different toothpastes containing 0 ppm fluoride (Group 1), 550 ppm fluoride (Group 2), and 1450 ppm fluoride (Group 3). The enamel surface hardness (VHN – Vickers Hardness) and the percentage change in hardness were measured at baseline, post-demineralization, and post-remineralization. Results: After demineralization, the mean VHN values were as follows: Group 1: 155.58 ± 68.28, Group 2: 108.25 ± 50.81, Group 3: 121.17 ± 48.41. After remineralization, the mean VHN values decreased in Group 1 but increased in Groups 2 and 3. Group 3, treated with toothpaste containing 1450 ppm fluoride, showed the highest mean VHN value post-remineralization (185.25 ± 81.22). Conclusion: Toothpaste containing 1450 ppm fluoride demonstrated a remineralization effect, increasing enamel surface hardness after demineralization in in-vitro. Toothpastes with 0 ppm and 550 ppm fluoride did not show this effect in in-vitro.
Keywords
Remineralization, toothpaste, 1450ppm fluoride, enamel surface, hardness
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References
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