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Date Published: 23/12/2021
Abstract Views: 389
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DOI: https://doi.org/10.51298/vmj.v507i2.1410
Issue
Vol. 507 No. 2 (2021)
Section
Các bài báo
How to Cite
Thị Duyên, N. ., & Tuấn Anh, B. . (2021). PLASMA IL-6 LEVEL AND HOMA2-IR INDEX IN TYPE 2 DIABETES PAINTIENTS. Vietnam Medical Journal, 507(2). https://doi.org/10.51298/vmj.v507i2.1410

PLASMA IL-6 LEVEL AND HOMA2-IR INDEX IN TYPE 2 DIABETES PAINTIENTS

Nguyễn Thị Duyên1,, Bùi Tuấn Anh1
1 Bach Mai Hospital

Main Article Content

Abstract

Type 2 diabetes mellitus (T2DM) has been one ot the most concerned health  problem globally. T2DM has a complex pathogenesis including insulin resistance. HOMA2-IR is a tool used for objective and non-invasive assessment of insulin resistance. Interleukin-6 is a cytokine related to obesity and insulin resistance in T2DM patients. In this study, we calculated HOMA2-IR index and measured IL-6 level of T2DM patients to compare with healthy control group and analyze the relation. Result: HOMA2-IR index in disease group was 2.92 ±1.75 and that of healthy control group was 1.52±0.68; while plasma IL-6 level in disease group was 3.15±2.19 pg/ml and control group was 1.85±0,91 pg/mL with p<0.05. There was a  proportional moderate relation betwwen plasma IL-6 level and HOMA2-IR index with r=0.569, p<0.01. Conclusion: There was a statistically significane in the difference between HOMA2-IR index and plasma IL-6 level of disease group and control group.

Article Details

Keywords

Type 2 diabetes mellitus (T2DM), plasma IL-6 level, HOMA2-IR index

References

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