EVALUATION OF THE OUTCOMES OF 3 – SNIP PUNCTOPLASTY WITH 5 – FLUOROURACIL APPLICATION IN THE TREATMENT OF ACQUIRED PUNCTAL STENOSIS

Bảo Phùng Mỹ, Nam Nguyễn Thành, Vân Biện Thị Cẩm, Trang Trịnh Xuân, Vy Lê Trần Thúy

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Abstract

Objective: To evaluate the outcomes of punctoplasty with the 3-snip procedure combined with the application of 5 fluorouracil (5FU) for acquired punctal stenosis after six months post-surgery. Study Methods: A prospective, comparative study was conducted from December 2023 to July 2024 at the Ophthalmic Plastic Surgery and Neuro-Ophthalmology Department, Ho Chi Minh City Eye Hospital. Patients diagnosed with grade 0 or 1 acquired punctal stenosis were enrolled and divided into two groups. Group 1 (30 eyes) receiving three-snip punctoplasty with 5FU and group 2 (30 eyes) without 5FU. A mini-Monoka S1.1500 stent was placed in all cases, with removal after three months. Patients were monitored over six months to assess success rates, functional outcomes, and complications. Results: The study included 60 eyes from 35 patients with an average age of 52 ± 12 years. Of these, 75% had grade 0 punctal stenosis, and 25% had grade 1 stenosis. After six months of surgery, functional success rates were 83.3% in the non 5FU group and 90% in the 5FU group. Anatomical success rates were 86.7% in the non-5FU group compared to 93.3% in the 5FU group. Overall success rates were 83.3% and 90% for the non 5FU and 5FU groups, respectively. Conclusion: The application of 5FU in three-snip punctoplasty significantly improves both functional and anatomical outcomes in treating acquired punctal stenosis.

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References

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