THỰC TRẠNG SỬ DỤNG THUỐC TRÊN NGƯỜI BỆNH MẮC BỆNH PHỔI TẮC NGHẼN MẠN TÍNH ĐIỀU TRỊ NGOẠI TRÚ VÀ CÁC YẾU TỐ LIÊN QUAN TẠI BỆNH VIỆN ĐA KHOA THÀNH PHỐ CẦN THƠ NĂM 2024

Abstract

Background: Chronic obstructive pulmonary disease (COPD) is currently one of the three leading causes of mortality worldwide. The condition is often accompanied by comorbidities that influence clinical outcomes and treatment strategies. Objectives: To assess the current status of drug utilization in outpatients with COPD at Can Tho City General Hospital in 2024. Methods: A retrospective, cross-sectional study was conducted in the prescriptions of COPD outpatients who visited and received treatment at Can Tho City General Hospital between January 2024 and April 2024. Results: Among 384 prescriptions reviewed, the most commonly prescribed medications included mucolytics (60.9%) and long-acting β2-agonists (LABA) and glucocorticosteroids (83.3%). Monotherapy was prescribed in 27.6% of cases. Overall, 87.3% of prescriptions were deemed appropriate. Significant differences were observed in the utilization of LABA/glucocorticosteroid combinations, mucolytics, antibiotics, and corticosteroids among subgroups stratified by health insurance status, presence of exacerbations, GOLD disease classification, ICS responsiveness, and eosinophil count (p < 0.05). Conclusion: The overall appropriateness of COPD treatment drug utilization in this study was relatively high. Factors such as health insurance status, COPD exacerbations, GOLD disease classification, ICS responsiveness, and eosinophil count were significantly associated with the utilization of LABA/glucocorticosteroids, mucolytics, antibiotics, and corticosteroids.