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STUDY ON CORONARY ARTERY LESION CHARACTERISTICS AND THE PROGNOSTIC VALUE OF NT-PROBNP AND HS-CRP LEVELS IN PREDICTING SEVERITY OF CORONARY ARTERY DISEASE IN ELDERLY PATIENTS WITH NON-ST-ELEVATION ACUTE CORONARY SYNDROME
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Abstract
Objectives: To determine the characteristics of coronary artery lesions and assess the prognostic value of NT-proBNP and hs-CRP in predicting the severity of coronary artery disease in elderly patients with ACS-NSTEMI. Materials and methods: Cross- A cross-sectional descriptive study was conducted on 99 elderly patients with ACS-NSTEMI at Ba Ria Hospital from June 2024 to February 2025. Results: Male patients accounted for 61.6%. The prevalence of comorbidities included: hypertension (89.9%), diabetes mellitus (29.3%), and dyslipidemia (74.7%). The most affected coronary artery was the left anterior descending (LAD) artery, seen in 89.9% of patients. 27.3% of patients had severe coronary artery lesions based on the Gensini score. NT-proBNP at a cut-off of 402.10 pg/mL had a sensitivity of 92.6% and specificity of 86.1% in predicting severe coronary artery lesions.hs-CRP at a cut-off of 19.35 mg/L had a sensitivity of 81.5% and specificity of 87.2% for the same outcome. Conclusion: In elderly patients with ACS-NSTEMI, NT-proBNP and hs-CRP levels at admission showed good predictive value for assessing the severity of coronary artery lesions.
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Keywords
Non-ST elevation acute coronary syndrome, elderly patiens, NT-proBNP level, hs-CRP level, severe coronary artery lesions
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