MỐI LIÊN QUAN SINH HÓA MÁU VỚI MỨC ĐỘ NẶNG Ở THAI PHỤ TIỀN SẢN GIẬT TẠI BỆNH VIỆN PHỤ SẢN THÀNH PHỐ CẦN THƠ

Abstract

Background: Preeclampsia is a leading cause of maternal and perinatal mortality worldwide. Certain laboratory tests may be useful in determining the extent of organ damage in affected patients, aiding obstetricians in timely diagnosis, effective disease management, and complication control. Objective: To determine the concentrations and correlation of selected blood biochemical markers with disease severity in preeclamptic pregnant women at Can Tho Obstetrics and Gynecology Hospital. Subjects and Methods: A cross-sectional descriptive study was conducted on 114 preeclamptic pregnant women diagnosed according to the Ministry of Health criteria at Can Tho Obstetrics and Gynecology Hospital from May to december 2024. Patients underwent clinical examination, medical history assessment, blood biochemical testing, preeclampsia severity evaluation, and treatment outcome monitoring. Results: The mean serum uric acid concentration was 363.8 ± 106.5 µmol/L; serum urea was 4.8 ± 7.8 mmol/L; serum creatinine was 58.8 ± 18.3 µmol/L; AST was 22.4 ± 15.3 U/L; ALT was 18.8 ± 20.1 U/L; and LDH was 289 ± 100.2 U/L. Higher levels of uric acid, creatinine, urea, AST, ALT, and LDH were significantly associated with an increased risk of severe preeclampsia (p<0.05). Conclusion: Blood biochemical parameters vary significantly with preeclampsia severity.