RESULTS OF TREATMENT METASTATIC PROSTATE CANCER BY ANDROGEN DEPRIVATION THERAPY

Nguyễn Anh Tuấn1,, Vũ Hồng Thăng1
1 Hanoi Medical University

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Abstract

Objective: To evaluate the efficiency of androgen deprivation therapy in metastatic prostate cancer. Patients and methods: Description study of 39 patients with metastatic prostate cancer who givenandrogen deprivation therapy between 2017 and June 2021. Results: Common clinical symptoms at the time of diagnosis: insomnia (66,7%), dysuria (69,2%), urinary frequency (56,4%), bone pain (59,0%). In which, 71,8% of patients choose surgical orchiectomy. After 3 months of treatment, the symptoms were significantly reduced: insomnia (17,9%), dysuria (20,5%), urinary frequency (5,1%), bone pain (28,2%). The mean progression-free survival (PFS) was 26,61±3,65months, in the surgical orchiectomy group was 22,62±3,45months, in the medical castration was 31,44±4,64 months, the difference was not statistically significant between two groups.  Conclusion: Androgen deprivation therapy is the cornerstone and effective treatment in metastatic prostate cancer.

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References

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