OUTCOMES OF PATIENTS WITH INTRACRANIAL HEMORRHAGE USING ORAL ANTICOAGULANTS AT THE STROKE CENTER OF BACH MAI HOSPITAL
Main Article Content
Abstract
Objective: Outcomes of intracerebral hemorrhage patients currently using oral anticoagulants. Compare patient characteristics between two groups of patients using DOACs and VKAs at the Stroke Center of Bach Mai Hospital. Subjects and Methods: Descriptive study of patients diagnosed with intracerebral hemorrhage and with a history of oral anticoagulant use at the Stroke Center of Bach Mai Hospital from October 2023 to October 2024. Outcomes and characteristics of intracerebral hemorrhage patients were described in both DOAC and VKA groups. Results: The study included 36 patients, of which 32 cases (88.9%) were using VKAs and 4 cases (11.1%) were using DOACs (including 3 Rivaroxaban, 1 Endoxaban). The ages was commonly found in elderly patients ≥65 years old, being treated for atrial fibrillation, with a mortality rate over 50%. There was no difference in clinical symptoms between the DOAC and VKA groups; however, INR and APTT indices in the VKA group were significantly higher than in the DOAC group (p<0.05). The most common bleeding location on CT-scan and MRI was above the cerebellum tentorium in both groups. Conclusion: Intracerebral hemorrhage in the VKA group was more common than in the DOAC group. Close monitoring of INR is necessary in patients using VKAs, especially in elderly subjects. Beyond mandatory indications, using DOACs as an alternative to VKAs should be considered when indicated.
Article Details
Keywords
anticoagulation, DOAC, VKA, intracerebral hemorrhage
References


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